Education:

Postdoctoral Fellow, Organic Chemistry, Ohio State University
Ph.D. Chemistry, University of North Carolina at Chapel Hill
B.S. Chemistry, Spelman College, Atlanta, Georgia

Research Interests:

Dr. Winstead is a Science, Technology, Engineering and Math (STEM) educator and researcher who uses her education and professional experience to encourage the development of student growth and to inspire and empower young, African-American scholars to reach their highest potential. Her philosophy is that a mentoring professor is most effective when teaching, research, and advising are intertwined together to provide a greater impact on the overall development of the student.
Over her career in synthesis, she has conducted basic and applied research in the areas of organic and organometallic synthetic chemistry. In addition to extensive organic synthesis experience, she has worked with rhenium, iridium and zinc based organometallics at various points in my synthetic career. Her specific areas of research include:

• Microwave Synthesis of Near-IR heptamethine Cyanine Dyes and pathogen detection. Applications include: 1) Characterization of the fluorescence lifetime and intensity changes of cyanine derivatives in various microenvironments, 2) Investigation of the microenvironmental changes and their ability to characterize the onset of cellular toxic events, 3) Development of pathogen biosensors, 
• Development of organorhenium tosylato compounds as a new class of anticancer drugs 
• STEM Education in the areas of critical thinking and curriculum redesign

Selected Publications:

• Winstead, A., McCarthy, P., Rice, D., Nyambura, G.W. “Linking Chemistry to Community: Integration of Culturally Responsive Teaching into General Chemistry I Laboratory in a Remote Setting”. J Chem. Ed. 2022 , (99) 1, 402-408 DOI: 10.1021/acs.jchemed.1c00494.
• Winstead, A., Huang, L.   “ Transitioning from a Traditional Lecture Style Organic Chemistry Classroom into a “Flipped” Classroom”. Broadening Participation in STEM, 2019 ISBN:  978-1-78756-908-9.

• Winstead, A., Nurudeen, D., Alabrash, K., Culmer-Gilbert, A., Akinbami, JP., Hinton, T., Parnell, S., Birsen,V., Krauss, C., Haynes, G., Abebe, F., Zhang, Y., McCarthy, P., Peng, J., Zavalij, P., Krause, J., Mandal,. S. “Organometallic Rhenium(I) Complexes of Some Non-Steroidal Anti-Inflammatory Drugs (ReNSAIDs): Synthesis, Characterizations, and DNA-Binding Studies”. A Comprehensive Guide to Non-Steroidal Anti-Inflammatory Drugs, 2021, ISBN: 978-1-53619-128-8.
• Winstead, A., Alabrash, K., Powell,. Parnell, S., Hinton, T., Odebode, T., Peng, J., Krause, J., Zavalij, P., Mandal,. S. “Microwave-assisted synthesis of organometallic rhenium (I) pentylcarbonato complexes: New synthon for carboxylato, sulfonato and chlorido complexes” J Organometallic Chem, 2021, (936) 15, 121718.
• Winstead, A., Huang, L.   “ Transitioning from a Traditional Lecture Style Organic Chemistry Classroom into a “Flipped” Classroom”. Broadening Participation in STEM, 2019 ISBN:  978-1-78756-908-9.
• Banerjee HN, Vaughan D, Boston A, Thorne G, Payne G, Sampson J, Manglik V, Olczak P, Powell BV, Winstead A, Shaw R, Mandal SK “The Effects of Synthesized Thenium Acetylsalicylate Compounds on Human Astrocytoma Cell Lines” J Cancer Sci The, 2018, 10 (2), 27-30 doi: 10.4172/1948-5956.1000512.
• Medley, J., Payne, P., Banerjee, H., Giri, D., Winstead, A., Wachira, J., Krause, J., Shaw, R., Pramanik, S., Mandal, S. "DNA-Binding and Cytotoxic Efficacy Studies of Organorhenium Pentylcarbonate Compounds", Molecular and Cellular Biochemistry, 2015, 398(1-2), 21-31.
• Grow, M., Winstead, A., Matthews, R. "Microwave synthesis of Sulfonated Cyanine Dyes for Use as Biosensors", 48th Annual Microwave Symposium Proceedings, 2014, ISBN: 978-0-956274748, New Orleans, LA. 58-61.
• Parson, C., Smith, V., Krauss, C., Banerjee, H., Reilly, C., Krause, J., Wachira, J., Giri, D., Winstead, A., Mandal, S., Brit. J. "Anticancer Properties of Novel Rhenium Pentylcarbanato Compounds against MDA-MB-468(HTB-132) Triple Node Negative Human Breast Cancer Cell Lines", Pharmaceut. Res. 2014, 4(3), 362-267.
• Winstead, A., Nyambura, G., Matthews, R., Toney, D. "Synthesis of Quaternary Heterocyclic Salts", Molecules, 2013, 18, 11, 14306-14319.
• Parson, C., Smith, V., Krauss, C., Banerjee, H., Reilly, C., Krause, J., Wachira, J., Giri, D., Winstead, A., Mandal, S., Brit, J. "The effect of novel rhenium compounds on lymphosarcoma, PC-3 prostate and myeloid leukemia cancer cell lines and an investigation on the DNA binding properties of one of these compounds through electronic spectroscopy", Bioproces. Biotechniq. 2013, 4, 141.
• Winstead, A. "General Chemistry Lab Manual. An Integrated Critical Thinking Approach" in press McGraw-Hill, 2013 ISBN: 1259117707
• Toney, D., Winstead, A. "A Redesigned General Chemistry Course to Improve Student Performance through Inquiry Based Learning", 2013, International Conference of Education, Research and Innovation Conference Proceedings, Madrid, Spain.
• Mbagu, M., Kebulu, D., Winstead, A., Pramanik, S., Banerjee, H., Iwunze, M., Wachira, J., Greco, G., Haynes, G., Sarkar, F., Hof, D., Pikeg, R., Mandal, S. "Fac-tricarbonyl(pentylcarbonato)(α-diimine)rhenium complexes, (CO)3(α-diimine)ReOC(O)OC5H11: one-pot synthesis from Re2(CO)10, characterization, and fluorescence and cytotoxicity studies." Inorganic Chemistry Communications, 2012, 21, 35-38.