PI:
Fahmi Khalifa
Co-PI(s):
Dept. or Schools:
Dept. of Electrical & Computer Engineering, School of Engineering
Affiliation:
Affiliated Faculty
Project Period:
November 2022 - continuing
Project Description:
Recent advances in artificial intelligence (AI) have significantly impacted various fields, especially medical image analysis for patient care. State-of-the-art (SOTA) AI tools analyze, fuse, and integrate medical images, data, and biomarkers to assess organ function. The need for physicians to provide patients with meaningful information about AI-rendered decisions has led to the development of explainable AI. This approach aims to improve understanding, justify decisions, introduce trust, and reduce bias. Trustworthy and explainable AI is emerging as a promising field for high-quality healthcare, offering human-comprehensible solutions for disease diagnosis, predictions, and recommended actions.
The primary goal of this project is to establish a multidisciplinary research program that integrates AI and Big Data in medicine to enhance research and workforce capabilities. Objectives include improving trust and reducing analysis bias, stimulating system design discussions, evaluating novel explainable AI for better disease diagnostics and prognostics, and enhancing research capacity at Morgan State University (MSU). The program also aims to encourage underrepresented students in STEM to engage in biomedical research addressing health disparities and minority health, and to prepare the next generation of minority researchers for AI/ML research.
The project seeks to translate SOTA AI/ML into practice through various applications, including AI Big Data for personalized medicine (PM). Personalized treatments based on individual medical data can reveal appropriate intervention targets and strategies, improving wellness and reducing healthcare costs. For example, AI can enhance the grading of age-related macular degeneration (AMD), a major cause of blindness in older adults. An interpretable diagnostic AI system could improve early AMD diagnosis, assess disease progression, and predict AMD advancement, enabling early intervention and better disease management. Another application is breast cancer diagnosis. Namely, to identify women at high risk, particularly those in underrepresented populations, and guide personalized screening, thereby increasing overall accuracy and helping to address health disparities and mitigate bias, in BC biopsy recommendations and outcomes.
Deliverables Completed:
Journal Articles:
[1] J. Dixon, O. Akinniyi, A. Abdelhamid, G. A. Saleh, Md. M. Rahman, and F. Khalifa, “A hybrid learning architecture for improved brain tumor recognition,” Algorithms, vol. 17, no. 16(221)–17 pp., 2024. https://www.mdpi.com/1999-4893/17/6/221
DOI: https://doi.org/10.3390/a17060221
[2] Y. Ismail, P. Okwan, F. Khalifa, A. Lawson, and F. Lacy, “Improving the practical skills of STEM students at a historically black college and university (HBCU),” J. Infrastructure, Policy, Develop., Vol. 8, no. 6–3507 (19 pp.), 2024.
https://systems.enpress-publisher.com/index.php/jipd/article/view/3507 ;
DOI: https://doi.org/10.24294/jipd.v8i6.3507
[3] E. Essel, A. Abdelhamid, M. Darwich, F. Khalifa, F. Lacy, and Y. Ismail, “High-Fidelity machine learning techniques for driver drowsiness detection,” Int. J. Comput. Digital Sys., vol. 16, no. 1, pp. 1444–1454, 2024. https://journals.uob.edu.bh/handle/123456789/5540
DOI: http://dx.doi.org/10.12785/ijcds/1601106
[4] A. Abdelhamid, O. Akinniyi, G. A. Saleh, W. Deabes, and F. Khalifa, “An ensemble neural architecture for lung diseases prediction using chest X-rays,” Int. J. Comput. Digital Sys., vol. 16, no. 1, pp. 1019–1028, 2024.
https://journals.uob.edu.bh/handle/123456789/5622
DOI: http://dx.doi.org/10.12785/ijcds/160174
[5] S. Naz, I. Kamran, S. Gul, F. Hadi, and F. Khalifa, “Multi-model fusion of CNNs for identification of Parkinson’s Disease using handwritten samples,” IEEE Access, vol. 11, pp. 135600–135608, 2023.
https://ieeexplore.ieee.org/document/10335677
DOI: https://doi.org/0.1109/ACCESS.2023.3337804
[6] O. Akinniyi, Md M. Rahman, H. S. Sandhu, A. El-Baz, and F. Khalifa, “Multi-stage classification of retinal OCT using multi-scale ensemble deep architecture” Bioengineering, vol. 10, no. 7 (16 pp.), 2023.
https://www.mdpi.com/2306-5354/10/7/823
DOI: https://doi.org/10.3390/bioengineering10070823
Conferences:
[1] Abdelhameed, O. Akinniyi, G. Saleh, and F. Khalifa, “Lung disease detection using scale-invariant weighted ensemble neural architecture,” In: Proc. Int. Conf. Intelli. Sys., Blockchain Commun. Techn. (ISBCom), Sharm El-Sheikh, Egypt, July 13–14, 2024 (Accepted)
[2] O. Akinniyi, J. Dixon, F. Khalifa, G. Saleh, and W. Deabes, “A vision transformer-based intelligent system for brain tumor diagnosis,” In: Proc. Int. Conf. Intelli. Sys., Blockchain Commun. Techn. (ISBCom), Sharm El-Sheikh, Egypt, July 13–14, 2024 (Accepted)
[3] O. Akinniyi, I. Razzak, Md M. Rahman, H. S. Sandhu, A. El-Baz, and F. Khalifa, “Multi-classification of retinal diseases using a pyramidal ensemble deep framework,” In: Proc. IEEE Int. Conf. Image Process. (ICIP), Kuala Lampur, Malaysia, October 8–11, 2023, pp. 1945–1949. (Oral presentation)
Other Deliverables:
[1] Invited talk:
Presenter: Fahmi Khalifa
Conference: National Symposium on Equitable AI,
Date/Location: April 5th, 2024, Baltimore, MD, USA
Title: Responsible AI for Biomedical Data Processing & Computing: Personalized Medicine
Link: https://equitableaisymposium.com/#agenda
[2] Keynote Speaker:
Presenter: Fahmi Khalifa
Conference: 3rd International Conference on Computing and Machine Intelligence (ICMI)
Date/Location: April 13th-14th, 2024, Central Michigan University (CMU), Michigan, USA
Title: AI Applications for Signal/Image Processing and Computing: Personalized Medicine
Link: https://www.icmiconf.com/keynote.html
[3] Keynote Speaker:
Presenter: Fahmi Khalifa
Conference: 1st International Conference on Intelligent Systems, Blockchain, and
Communication Technologies
Date/Location: July 13th-14th, 2024, Sharm El-Sheikh, Egypt
Title: AI Applications for Signal/Image Processing and Computing: Personalized Medicine
Link: https://www.isbcomtech.com/speaker.html
[4] ISBCom Conference Oral Presentation:
Presenter: Oluwatunmise Akinniyi
Conference: International Conference on Intelligent Systems, Blockchain, and
Communication Technologies
Date/Location: July 13th-14th, 2024, Sharm El-Sheikh, Egypt
Title: vision transformer-based intelligent system for brain tumor diagnosis
[5] ISBCom Conference Oral Presentation:
Presenter: Abeer Abdelhameed
Conference: International Conference on Intelligent Systems, Blockchain, and
Communication Technologies
Date/Location: July 13th-14th, 2024, Sharm El-Sheikh, Egypt
Title: Lung disease detection using scale-invariant weighted ensemble neural architecture
[6] Thesis Defense:
Oluwatunmise Akinniyi
Thesis title: Multi-stage classification of retinal optical coherence tomography (OCT)
images using multi-scale ensemble deep architecture.
M.Sc., graduated Fall’23
[7] ICIP Conference Oral Presentation:
Presenter: Oluwatunmise Akinniyi
Conference: IEEE International Conference on Image Processing
Date/Location: October 8th-11th, 2023, Kuala Lumpur, Malaysia
Title: Multi-Classification of Retinal Diseases Using a Pyramidal Ensemble Deep
Framework